Mitochondrial estrogen receptors alter mitochondrial priming and response to endocrine therapy in breast cancer cells

Abstract Breast cancer is the most common cancer with a high rate of mortality and morbidity among women worldwide. Estrogen receptor status is an important prognostic factor and endocrine therapy is the choice of first-line treatment in ER-positive breast cancer. However, most tumors develop resist...

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Bibliographic Details
Main Authors: Bahriye Karakas, Yeliz Aka, Asli Giray, Sehime Gulsun Temel, Ufuk Acikbas, Huveyda Basaga, Ozgur Gul, Ozgur Kutuk
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00573-2