Mitochondrial estrogen receptors alter mitochondrial priming and response to endocrine therapy in breast cancer cells
Abstract Breast cancer is the most common cancer with a high rate of mortality and morbidity among women worldwide. Estrogen receptor status is an important prognostic factor and endocrine therapy is the choice of first-line treatment in ER-positive breast cancer. However, most tumors develop resist...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-07-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-021-00573-2 |