The synthetic melanocortin (CKPV)2 exerts anti-fungal and anti-inflammatory effects against Candida albicans vaginitis via inducing macrophage M2 polarization.

The synthetic melanocortin (CKPV)2 exerts anti-fungal and anti-inflammatory effects against Candida albicans vaginitis via inducing macrophage M2 polarization.

In this study, we examined anti-fungal and anti-inflammatory effects of the synthetic melanocortin peptide (Ac-Cys-Lys-Pro-Val-NH2)2 or (CKPV)2 against Candida albicans vaginitis. Our in vitro results showed that (CKPV)2 dose-dependently inhibited Candida albicans colonies formation. In a rat Candid...

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Bibliographic Details
Main Authors: Hai-xia Ji, Yu-lian Zou, Jing-jing Duan, Zhi-rong Jia, Xian-jing Li, Zhuo Wang, Li Li, Yong-wen Li, Gen-yan Liu, Ming-qing Tong, Xiao-yi Li, Guo-hui Zhang, Xiang-rong Dai, Ling He, Zhi-yu Li, Cong Cao, Yong Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23457491/pdf/?tool=EBI

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