Risk factors for nonadherence to antiretroviral therapy in patients with HIV infection and ways of identification

• Main Authors: ON Fedyaeva, NA Sirota
• Format: Article
• Language: Russian
• Published: Remedium Group LLC 2014-12-01
• Series: Медицинский совет
• Subjects: вич-инфекция; кластерный анализ; факторы приверженности; антиретровирусная терапия; приверженность антиретровирусной терапии; hiv infection; cluster analysis; adherence factors; antiretroviral therapy; adherence to antiretroviral therapy
• Online Access: https://www.med-sovet.pro/jour/article/view/606
• ISSN: 2079-701X; 2658-5790

The aim of the study was to develop a clinically feasible method for predicting adherence of HIV patients to antiretroviral therapy based on the study of their personality and psychological characteristics, relationships with others and social status. In the course of the study, clusters of ART adherence were statistically identified and factors which could facilitate identification of patient's reference to a particular cluster of adherence were revealed. The objective of this section is to develop questionnaires to be filled jointly by patient and physician, allowing to identify risk factors for ART nonadherence in patient and to make projections. Conclusion: on the basis of the defined risk factors, it became possible to compile a questionnaire for joint filling by patient and physician, which allows to determine the degree of risk of nonadherence to ART with about 70% of diagnostic accuracy and provide the HIV-infected patient with medical recommendations.