Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives

Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives

2,3-Diphenyl quinoxaline (SI) was fused with 2-amino benzothiazoles (SII) by a methylene bridge, which was then allowed for acetylation. The acetylated product (SIV) was made to react with different aromatic aldehydes to give chalcones (SV1-SV5). Chalcones refluxed with substituted acid hydrazides t...

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Main Authors: CH. Sridevi, K. Balaji, A. Naidu, R. Sudhakaran
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2009/324358
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spelling doaj-44a68244b9f848a59917ba722e8a6f012020-11-24T23:11:57ZengHindawi LimitedE-Journal of Chemistry0973-49452090-98102009-01-016386687010.1155/2009/324358Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline DerivativesCH. Sridevi0K. Balaji1A. Naidu2R. Sudhakaran3Department of Pharmaceutical Chemistry, Geethanjali College of Pharmacy, Cheeryal(V), Keesara(M), Hyderabad.501301, IndiaDepartment of Pharmaceutical Chemistry, Geethanjali College of Pharmacy, Cheeryal(V), Keesara(M), Hyderabad.501301, IndiaDepartment of Pharmaceutical Chemistry, Geethanjali College of Pharmacy, Cheeryal(V), Keesara(M), Hyderabad.501301, IndiaDepartment of Pharmaceutical Chemistry, Geethanjali College of Pharmacy, Cheeryal(V), Keesara(M), Hyderabad.501301, India2,3-Diphenyl quinoxaline (SI) was fused with 2-amino benzothiazoles (SII) by a methylene bridge, which was then allowed for acetylation. The acetylated product (SIV) was made to react with different aromatic aldehydes to give chalcones (SV1-SV5). Chalcones refluxed with substituted acid hydrazides to afford different phenyl pyrazolo benzothiazolo quinoxaline derivatives (SVI1-SVI15). The structure of chalcones and phenyl pyrazolo benzothiazolo quinoxaline derivatives were confirmed by M.P, TLC and spectral data. All the synthesized compounds were screened for their antimicrobial activities.http://dx.doi.org/10.1155/2009/324358
collection DOAJ
language English
format Article
sources DOAJ
author CH. Sridevi
K. Balaji
A. Naidu
R. Sudhakaran
spellingShingle CH. Sridevi
K. Balaji
A. Naidu
R. Sudhakaran
Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives
E-Journal of Chemistry
author_facet CH. Sridevi
K. Balaji
A. Naidu
R. Sudhakaran
author_sort CH. Sridevi
title Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives
title_short Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives
title_full Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives
title_fullStr Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives
title_full_unstemmed Antimicrobial Evaluation and Synthesis of Some Phenylpyrazolo benzothiazolo quinoxaline Derivatives
title_sort antimicrobial evaluation and synthesis of some phenylpyrazolo benzothiazolo quinoxaline derivatives
publisher Hindawi Limited
series E-Journal of Chemistry
issn 0973-4945
2090-9810
publishDate 2009-01-01
description 2,3-Diphenyl quinoxaline (SI) was fused with 2-amino benzothiazoles (SII) by a methylene bridge, which was then allowed for acetylation. The acetylated product (SIV) was made to react with different aromatic aldehydes to give chalcones (SV1-SV5). Chalcones refluxed with substituted acid hydrazides to afford different phenyl pyrazolo benzothiazolo quinoxaline derivatives (SVI1-SVI15). The structure of chalcones and phenyl pyrazolo benzothiazolo quinoxaline derivatives were confirmed by M.P, TLC and spectral data. All the synthesized compounds were screened for their antimicrobial activities.
url http://dx.doi.org/10.1155/2009/324358
work_keys_str_mv AT chsridevi antimicrobialevaluationandsynthesisofsomephenylpyrazolobenzothiazoloquinoxalinederivatives
AT kbalaji antimicrobialevaluationandsynthesisofsomephenylpyrazolobenzothiazoloquinoxalinederivatives
AT anaidu antimicrobialevaluationandsynthesisofsomephenylpyrazolobenzothiazoloquinoxalinederivatives
AT rsudhakaran antimicrobialevaluationandsynthesisofsomephenylpyrazolobenzothiazoloquinoxalinederivatives
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