Bioengineered miR-328-3p modulates GLUT1-mediated glucose uptake and metabolism to exert synergistic antiproliferative effects with chemotherapeutics

Bioengineered miR-328-3p modulates GLUT1-mediated glucose uptake and metabolism to exert synergistic antiproliferative effects with chemotherapeutics

MicroRNAs (miRNAs or miRs) are small noncoding RNAs derived from genome to control target gene expression. Recently we have developed a novel platform permitting high-yield production of bioengineered miRNA agents (BERA). This study is to produce and utilize novel fully-humanized BERA/miR-328-3p mol...

Full description

Bibliographic Details
Main Authors: Wanrong Yi, Mei-Juan Tu, Zhenzhen Liu, Chao Zhang, Neelu Batra, Ai-Xi Yu, Ai-Ming Yu
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Acta Pharmaceutica Sinica B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383519309086

Similar Items

Similar Items