Zika virus encephalitis in immunocompetent mice is dominated by innate immune cells and does not require T or B cells

Zika virus encephalitis in immunocompetent mice is dominated by innate immune cells and does not require T or B cells

Abstract Background Until the end of the twentieth century, Zika virus (ZIKV) was thought to cause a mostly mild, self-limiting disease in humans. However, as the geographic distribution of ZIKV has shifted, so too has its pathogenicity. Modern-day ZIKV infection is now known to cause encephalitis,...

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Bibliographic Details
Main Authors: Emina Hayashida, Zheng Lung Ling, Thomas M. Ashhurst, Barney Viengkhou, So Ri Jung, Pattama Songkhunawej, Phillip K. West, Nicholas J. C. King, Markus J. Hofer
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Neuroinflammation
Subjects:
Zika virus
Microglia
Monocyte
Neutrophil
Encephalitis
Innate immunity
Online Access:http://link.springer.com/article/10.1186/s12974-019-1566-5

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http://link.springer.com/article/10.1186/s12974-019-1566-5

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