Advances in the Assembly Model of Bacterial Type IVB Secretion Systems

Advances in the Assembly Model of Bacterial Type IVB Secretion Systems

Bacterial type IV secretion systems (T4SSs) are related to not only secretion of effector proteins and virulence factors, but also to bacterial conjugation systems that promote bacterial horizontal gene transfer. The subgroup T4BSS, with a unique mosaic architecture system, consists of nearly 30 pro...

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Main Authors: Shan Wang, Dan Wang, Dan Du, Shanshan Li, Wei Yan
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Applied Sciences
Subjects:
T4BSS
core complex
mosaic architecture
Online Access:https://www.mdpi.com/2076-3417/8/12/2368
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spelling doaj-447c87def6eb4cfabf3eacd0d99651b32020-11-24T21:28:54ZengMDPI AGApplied Sciences2076-34172018-11-01812236810.3390/app8122368app8122368Advances in the Assembly Model of Bacterial Type IVB Secretion SystemsShan Wang0Dan Wang1Dan Du2Shanshan Li3Wei Yan4Department of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an 710049, ChinaDepartment of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an 710049, ChinaDepartment of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an 710049, ChinaDepartment of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an 710049, ChinaDepartment of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an 710049, ChinaBacterial type IV secretion systems (T4SSs) are related to not only secretion of effector proteins and virulence factors, but also to bacterial conjugation systems that promote bacterial horizontal gene transfer. The subgroup T4BSS, with a unique mosaic architecture system, consists of nearly 30 proteins that are similar to those from other secretory systems. Despite being intensively studied, the secretion mechanism of T4BSS remains unclear. This review systematically summarizes the protein composition, coding gene set, core complex, and protein interactions of T4BSS. The interactions of proteins in the core complex of the system and the operation mechanism between each element needs to be further studied.https://www.mdpi.com/2076-3417/8/12/2368T4BSScore complexmosaic architecture
collection DOAJ
language English
format Article
sources DOAJ
author Shan Wang
Dan Wang
Dan Du
Shanshan Li
Wei Yan
spellingShingle Shan Wang
Dan Wang
Dan Du
Shanshan Li
Wei Yan
Advances in the Assembly Model of Bacterial Type IVB Secretion Systems
Applied Sciences
T4BSS
core complex
mosaic architecture
author_facet Shan Wang
Dan Wang
Dan Du
Shanshan Li
Wei Yan
author_sort Shan Wang
title Advances in the Assembly Model of Bacterial Type IVB Secretion Systems
title_short Advances in the Assembly Model of Bacterial Type IVB Secretion Systems
title_full Advances in the Assembly Model of Bacterial Type IVB Secretion Systems
title_fullStr Advances in the Assembly Model of Bacterial Type IVB Secretion Systems
title_full_unstemmed Advances in the Assembly Model of Bacterial Type IVB Secretion Systems
title_sort advances in the assembly model of bacterial type ivb secretion systems
publisher MDPI AG
series Applied Sciences
issn 2076-3417
publishDate 2018-11-01
description Bacterial type IV secretion systems (T4SSs) are related to not only secretion of effector proteins and virulence factors, but also to bacterial conjugation systems that promote bacterial horizontal gene transfer. The subgroup T4BSS, with a unique mosaic architecture system, consists of nearly 30 proteins that are similar to those from other secretory systems. Despite being intensively studied, the secretion mechanism of T4BSS remains unclear. This review systematically summarizes the protein composition, coding gene set, core complex, and protein interactions of T4BSS. The interactions of proteins in the core complex of the system and the operation mechanism between each element needs to be further studied.
topic T4BSS
core complex
mosaic architecture
url https://www.mdpi.com/2076-3417/8/12/2368
work_keys_str_mv AT shanwang advancesintheassemblymodelofbacterialtypeivbsecretionsystems
AT danwang advancesintheassemblymodelofbacterialtypeivbsecretionsystems
AT dandu advancesintheassemblymodelofbacterialtypeivbsecretionsystems
AT shanshanli advancesintheassemblymodelofbacterialtypeivbsecretionsystems
AT weiyan advancesintheassemblymodelofbacterialtypeivbsecretionsystems
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