The majority of primate-specific regulatory sequences are derived from transposable elements.
Although emerging evidence suggests that transposable elements (TEs) have contributed novel regulatory elements to the human genome, their global impact on transcriptional networks remains largely uncharacterized. Here we show that TEs have contributed to the human genome nearly half of its active e...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-05-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3649963?pdf=render |