Procyanidin trimer C1 reactivates latent HIV as a triple combination therapy with kansui and JQ1.

Although anti-retroviral therapies have greatly extended the lives of HIV infected individuals, current treatments are unable to completely eliminate virally infected cells. A number of latency reversing agents have been proposed for use in a "shock and kill" strategy to reactivate latent...

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Bibliographic Details
Main Authors: Daniele C Cary, B Matija Peterlin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6258234?pdf=render