Optimising PLGA-PEG Nanoparticle Size and Distribution for Enhanced Drug Targeting to the Inflamed Intestinal Barrier

Optimising PLGA-PEG Nanoparticle Size and Distribution for Enhanced Drug Targeting to the Inflamed Intestinal Barrier

Oral nanomedicines are being investigated as an innovative strategy for targeted drug delivery to treat inflammatory bowel diseases. Preclinical studies have shown that nanoparticles (NPs) can preferentially penetrate inflamed intestinal tissues, allowing for targeted drug delivery. NP size is a cri...

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Bibliographic Details
Main Authors: Lauren J. Mohan, Lauren McDonald, Jacqueline S. Daly, Zebunnissa Ramtoola
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceutics
Subjects:
IBD
nanomedicine
PLGA-PEG
nanoparticles
differential centrifugation
cellular uptake
Online Access:https://www.mdpi.com/1999-4923/12/11/1114

Internet

https://www.mdpi.com/1999-4923/12/11/1114

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