The expanding spectrum of neurological disorders of phosphoinositide metabolism

Phosphoinositides (PIPs) are a ubiquitous group of seven low-abundance phospholipids that play a crucial role in defining localized membrane properties and that regulate myriad cellular processes, including cytoskeletal remodeling, cell signaling cascades, ion channel activity and membrane traffic....

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Bibliographic Details
Main Authors: Jonathan R. Volpatti, Almundher Al-Maawali, Lindsay Smith, Aqeela Al-Hashim, Julie A. Brill, James J. Dowling
Format: Article
Language:English
Published: The Company of Biologists 2019-08-01
Series:Disease Models & Mechanisms
Subjects:
ALS
Online Access:http://dmm.biologists.org/content/12/8/dmm038174