High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody.

Chronic hepatitis C virus (HCV) infection is the most common cause of end-stage liver disease, often leading to liver transplantation, in which case circulating virions typically infect the transplanted liver within hours and viral concentrations can quickly exceed pre-transplant levels. MBL-HCV1 is...

Full description

Bibliographic Details
Main Authors: Gregory J Babcock, Sowmya Iyer, Heidi L Smith, Yang Wang, Kirk Rowley, Donna M Ambrosino, Phillip D Zamore, Brian G Pierce, Deborah C Molrine, Zhiping Weng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4067308?pdf=render