A truncated p53 in human lung cancer cells as a critical determinant of proliferation and invasiveness
As a transcription factor, p53 must accumulate in the nucleus to be effective. Signals related to nuclear localization are distributed mainly in the C-terminal of p53. So these nuclear location domains were reserved and the other part of the C-terminal was removed in this study. We investigated whet...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
IOS Press
2017-05-01
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| Series: | Tumor Biology |
| Online Access: | https://doi.org/10.1177/1010428317703824 |