Versatile synthesis of amino acid functionalized nucleosides via a domino carboxamidation reaction

Functionalized oligonucleotides have recently gained increased attention for incorporation in modified nucleic acid structures both for the design of aptamers with enhanced binding properties as well as the construction of catalytic DNA and RNA. As a shortcut alternative to the incorporation of mult...

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Bibliographic Details
Main Authors: Vicky Gheerardijn, Jos Van den Begin, Annemieke Madder
Format: Article
Language:English
Published: Beilstein-Institut 2014-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.10.268