Focal segmental glomerulosclerosis as the sole renal lesion in <i>Wegener′s granulomatosis</i>
Wegener′s granulomatosis usually presents with focal necrotizing glomerulonephritis with crescents. We present here a 45-year old man who was treated for tuberculosis and later pre-sented with bilateral ankle swelling. His serum creatinine was 2.4 mg/dL and urine analysis revealed hematur...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2010-01-01
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| Series: | Saudi Journal of Kidney Diseases and Transplantation |
| Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2010;volume=21;issue=6;spage=1118;epage=1121;aulast=Ibrahim |
| Summary: | Wegener′s granulomatosis usually presents with focal necrotizing glomerulonephritis with crescents. We present here a 45-year old man who was treated for tuberculosis and later pre-sented with bilateral ankle swelling. His serum creatinine was 2.4 mg/dL and urine analysis revealed hematuria and proteinuria. His 24-hour urine protein excretion was 1.9 g. Anti neutrophil cytoplasmic antibodies (ANCA) test was positive with cytoplasmic florescence pattern. Renal biopsy revealed focal segmental sclerosis with no active vasculitis and lung biopsy revealed extensive breakdown with cavitations and scattered granulomas. |
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| ISSN: | 1319-2442 |