Recent Advances in Understanding Amino Acid Sensing Mechanisms that Regulate mTORC1

Recent Advances in Understanding Amino Acid Sensing Mechanisms that Regulate mTORC1

The mammalian target of rapamycin (mTOR) is the central regulator of mammalian cell growth, and is essential for the formation of two structurally and functionally distinct complexes: mTORC1 and mTORC2. mTORC1 can sense multiple cues such as nutrients, energy status, growth factors and hormones to c...

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Bibliographic Details
Main Authors: Liufeng Zheng, Wei Zhang, Yuanfei Zhou, Fengna Li, Hongkui Wei, Jian Peng
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:International Journal of Molecular Sciences
Subjects:
mTORC1
amino acids
membrane transceptor
membrane receptor
sensor
Online Access:http://www.mdpi.com/1422-0067/17/10/1636

Internet

http://www.mdpi.com/1422-0067/17/10/1636

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