Susac syndrome and pregnancy: a review of published cases and considerations for patient management

Susac syndrome (SuS) is a rare autoimmune endotheliopathy leading to hearing loss, branch retinal artery occlusions and encephalopathy. Young females are more frequently affected than males, making counselling for family planning an important issue. We reviewed published cases on SuS during pregnanc...

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Main Authors: Barbara Willekens, Ilka Kleffner
Format: Article
Language:English
Published: SAGE Publishing 2021-01-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756286420981352
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spelling doaj-44186a5566fc4b76a1999407c2c46e962021-02-03T17:34:04ZengSAGE PublishingTherapeutic Advances in Neurological Disorders1756-28642021-01-011410.1177/1756286420981352Susac syndrome and pregnancy: a review of published cases and considerations for patient managementBarbara WillekensIlka KleffnerSusac syndrome (SuS) is a rare autoimmune endotheliopathy leading to hearing loss, branch retinal artery occlusions and encephalopathy. Young females are more frequently affected than males, making counselling for family planning an important issue. We reviewed published cases on SuS during pregnancy or in the postpartum period, and selected 27 reports describing the details of 33 patients with SuS. Treatment options and implications for pregnancy and breastfeeding are discussed. We propose new areas for research and suggest a management strategy.https://doi.org/10.1177/1756286420981352
collection DOAJ
language English
format Article
sources DOAJ
author Barbara Willekens
Ilka Kleffner
spellingShingle Barbara Willekens
Ilka Kleffner
Susac syndrome and pregnancy: a review of published cases and considerations for patient management
Therapeutic Advances in Neurological Disorders
author_facet Barbara Willekens
Ilka Kleffner
author_sort Barbara Willekens
title Susac syndrome and pregnancy: a review of published cases and considerations for patient management
title_short Susac syndrome and pregnancy: a review of published cases and considerations for patient management
title_full Susac syndrome and pregnancy: a review of published cases and considerations for patient management
title_fullStr Susac syndrome and pregnancy: a review of published cases and considerations for patient management
title_full_unstemmed Susac syndrome and pregnancy: a review of published cases and considerations for patient management
title_sort susac syndrome and pregnancy: a review of published cases and considerations for patient management
publisher SAGE Publishing
series Therapeutic Advances in Neurological Disorders
issn 1756-2864
publishDate 2021-01-01
description Susac syndrome (SuS) is a rare autoimmune endotheliopathy leading to hearing loss, branch retinal artery occlusions and encephalopathy. Young females are more frequently affected than males, making counselling for family planning an important issue. We reviewed published cases on SuS during pregnancy or in the postpartum period, and selected 27 reports describing the details of 33 patients with SuS. Treatment options and implications for pregnancy and breastfeeding are discussed. We propose new areas for research and suggest a management strategy.
url https://doi.org/10.1177/1756286420981352
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