A Single Protein S-acyl Transferase Acts through Diverse Substrates to Determine Cryptococcal Morphology, Stress Tolerance, and Pathogenic Outcome.
Cryptococcus neoformans is an opportunistic yeast that kills over 625,000 people yearly through lethal meningitis. Host phagocytes serve as the first line of defense against this pathogen, but fungal engulfment and subsequent intracellular proliferation also correlate with poor patient outcome. Defi...
Main Authors: | Felipe H Santiago-Tirado, Tao Peng, Meng Yang, Howard C Hang, Tamara L Doering |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-05-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4430228?pdf=render |
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