Trifolium pratense L. (red clover) extract and doxorubicin synergistically inhibits proliferation of 4T1 breast cancer in tumor‐bearing BALB/c mice through modulation of apoptosis and increase antioxidant and anti‐inflammatory related pathways

Trifolium pratense L. (red clover) extract and doxorubicin synergistically inhibits proliferation of 4T1 breast cancer in tumor‐bearing BALB/c mice through modulation of apoptosis and increase antioxidant and anti‐inflammatory related pathways

Abstract Therapeutic strategies against triple‐negative breast cancer (TNBC) are associated with drug‐induced toxicities. The tropical edible red clover (Trifolium pratense L.) is rich in polyphenolic compounds which confer the plant potential anticancer properties. The aim of this study was to inve...

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Bibliographic Details
Main Authors: Mohsen Akbaribazm, Mohammad Rasoul Khazaei, Mozafar Khazaei
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Food Science & Nutrition
Subjects:
4T1 cell
apoptosis
breast cancer
doxorubicin
isoflavone
Trifolium pratense L.
Online Access:https://doi.org/10.1002/fsn3.1724

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