Cytokine status of patients with acute sluggish odontogenic osteomyelitis of the jaw

• Main Authors: Неонилла Гавриловна Баранник, Сурен Диасович Варжапетян
• Format: Article
• Language: English
• Published: PC Technology Center 2015-01-01
• Series: ScienceRise
• Subjects: immunological status; acute odontogenic osteomyelitis of the jaws; interleukins
• Online Access: http://journals.uran.ua/sciencerise/article/view/36524

<p>The content of IL-1β in the serum level was 1,823±0,300 (p&lt;0.001), which is approximately 14.7 times the value of this indicator in healthy individuals - control group (0,124±0,026). The concentration of TNFα in the blood of healthy individuals was 0,196±0,023, while in patients with acute odontogenic osteomyelitis occurs without acute clinical symptoms, observed an increase in the corresponding rate to 2,752±0,624 (p&lt;0.001), almost 14 times. In the study group, it was also a sevenfold increase in the synthesis of IL-6 (22,224±8,244; p&lt;0.001) compared with the control group (3,158±0,214).</p><p>The content of anti-inflammatory factors, immunological protection of organism (IL-4) in patients with odontogenic osteomyelitis at admission was 0,462±0,064, which was a statistically significant increase (p&gt;0,05) compared with those in the control group – 0,416±0,058</p>