Durable CRISPR-Based Epigenetic Silencing
Development of CRISPR-based epigenome editing tools is important for the study and engineering of biological behavior. Here, we describe the design of a reporter system for quantifying the ability of CRISPR epigenome editors to produce a stable gene repression. We characterize the dynamics of durabl...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Association for the Advancement of Science
2021-01-01
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| Series: | BioDesign Research |
| Online Access: | http://dx.doi.org/10.34133/2021/9815820 |