The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye

The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye

Embryopathies that develop as a consequence of maternal diabetes have been studied intensely in both experimental and clinical scenarios. Accordingly, hyperglycaemia has been shown to downregulate the expression of elements in the non-canonical Wnt-PCP pathway, such as the Dishevelled-associated act...

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Bibliographic Details
Main Authors:	Beatriz López-Escobar, David A. Cano, Anabel Rojas, Beatriz de Felipe, Francisco Palma, José A. Sánchez-Alcázar, Deborah Henderson, Patricia Ybot-González
Format:	Article
Language:	English
Published:	The Company of Biologists 2015-02-01
Series:	Disease Models & Mechanisms
Subjects:	Diabetes Wnt-PCP pathway Daam1 Eye defects Heart defects Neural tube defects
Online Access:	http://dmm.biologists.org/content/8/2/157

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