Isotopic Evidence for Disrupted Copper Metabolism in Amyotrophic Lateral Sclerosis

Isotopic Evidence for Disrupted Copper Metabolism in Amyotrophic Lateral Sclerosis

Summary: Redox-active metals are thought to be implicated in neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). To address this point, we measured the concentrations of 12 elements and, for the first time, the stable isotope compositions of copper (redox-active) and zinc (redo...

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Bibliographic Details
Main Authors: Lucie Sauzéat, Emilien Bernard, Armand Perret-Liaudet, Isabelle Quadrio, Alain Vighetto, Pierre Krolak-Salmon, Emmanuel Broussolle, Pascal Leblanc, Vincent Balter
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218301111

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