Activation of group II metabotropic glutamate receptors blocks zinc release from hippocampal mossy fibers

Activation of group II metabotropic glutamate receptors blocks zinc release from hippocampal mossy fibers

BACKGROUND: The hippocampal CA3 area contains large amounts of vesicular zinc in the mossy fiber terminals which is released during synaptic activity, depending on presynaptic calcium. Another characteristic of these synapses is the presynaptic localization of high concentrations of group II metabot...

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Bibliographic Details
Main Authors: Carlos M Matias, Jose C Dionísio, Peter Saggau, Maria Emilia Quinta-Ferreira
Format: Article
Language:English
Published: BMC 2014-01-01
Series:Biological Research
Subjects:
Zinc
Neurotransmission
Glutamatergic
Co-release
Metabotropic fluorescence
Inhibition
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100067&lng=en&tlng=en

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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100067&lng=en&tlng=en

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