Structural and dynamic characterization of the C313Y mutation in Myostatin dimeric protein, responsible for the double muscle phenotype in Piedmontese cattle

Structural and dynamic characterization of the C313Y mutation in Myostatin dimeric protein, responsible for the double muscle phenotype in Piedmontese cattle

The knowledge of the molecular effects of the C313Y mutation, responsible for the double muscle phenotype in Piedmontese cattle, can help understanding the actual mechanism of phenotype determination and paves the route for a better modulation of the positive effects of this economic important pheno...

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Bibliographic Details
Main Authors: Silvia eBongiorno, Alessio eValentini, Giovanni eChillemi
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Genetics
Subjects:
Myostatin
molecular dynamics
Double muscling
Piedmontese mutation
C313Y
dimer asymmetry
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00014/full

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