Animal Models for Human Polycystic Ovary Syndrome (PCOS) Focused on the Use of Indirect Hormonal Perturbations: A Review of the Literature

Animal Models for Human Polycystic Ovary Syndrome (PCOS) Focused on the Use of Indirect Hormonal Perturbations: A Review of the Literature

Hormonal disturbances, such as hyperandrogenism, are considered important for developing polycystic ovary syndrome (PCOS) in humans. Accordingly, directly hormone-regulated animal models are widely used for studying PCOS, as they replicate several key PCOS features. However, the pathogenesis and tre...

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Bibliographic Details
Main Authors: Youngjae Ryu, Sung Woo Kim, Yoon Young Kim, Seung-Yup Ku
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
polycystic ovary syndrome
animal models
ovary
pathogenesis
Online Access:https://www.mdpi.com/1422-0067/20/11/2720

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