IFN signaling: how a non-canonical model led to the development of IFN mimetics

IFN signaling: how a non-canonical model led to the development of IFN mimetics

The classical model of cytokine signaling dominates our view of specific gene activation by cytokines such as the interferons (IFNs). The importance of the model extends beyond cytokines and applies to hormones such as growth hormone (GH) and insulin, and growth factors such as epidermal growth fac...

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Bibliographic Details
Main Authors: Howard M Johnson, Ezra Neptune Noon-Song, Rea eDabelic, Chulbul M. Ahmed
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Immunology
Subjects:
Cytokines
Interferons
JAK/STAT signaling pathway
interferon mimetics
interferon receptor
interferon signaling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00202/full

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