Pristanic acid and phytanic acid: naturally occurring ligands for the nuclear receptor peroxisome proliferator-activated receptor α
Phytanic acid and pristanic acid are branched-chain fatty acids, present at micromolar concentrations in the plasma of healthy individuals. Here we show that both phytanic acid and pristanic acid activate the peroxisome proliferator-activated receptor α (PPARα) in a concentration-dependent manner. A...
Main Authors: | Anna W.M. Zomer, Bart van der Burg, Gerbert A. Jansen, Ronald J.A. Wanders, Bwee Tien Poll-The, Paul T. van der Saag |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2000-11-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520319738 |
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