Pristanic acid and phytanic acid: naturally occurring ligands for the nuclear receptor peroxisome proliferator-activated receptor α

Phytanic acid and pristanic acid are branched-chain fatty acids, present at micromolar concentrations in the plasma of healthy individuals. Here we show that both phytanic acid and pristanic acid activate the peroxisome proliferator-activated receptor α (PPARα) in a concentration-dependent manner. A...

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Bibliographic Details
Main Authors: Anna W.M. Zomer, Bart van der Burg, Gerbert A. Jansen, Ronald J.A. Wanders, Bwee Tien Poll-The, Paul T. van der Saag
Format: Article
Language:English
Published: Elsevier 2000-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520319738