Identification of PD-L2, B7-H3 and CTLA-4 immune checkpoint proteins in genetic subtypes of meningioma

Identification of PD-L2, B7-H3 and CTLA-4 immune checkpoint proteins in genetic subtypes of meningioma

Meningioma is the most common brain tumor in adults. Surgical resection remains the primary treatment. No chemotherapy exists. However, gene mutations now could explain ~ 80% of meningioma and targeted therapies based on these are being investigated. Furthermore, with the recent discovery of PD-L1 i...

Full description

Bibliographic Details
Main Authors: Dustin T Proctor, Zeel Patel, Sanju Lama, Lothar Resch, Guido van Marle, Garnette R Sutherland
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:OncoImmunology
Subjects:
meningioma
immune checkpoint protein
pd-l1
pd-l2
b7-h3
ctla-4
pi3k/akt/mtor
immunotherapy
brain tumor
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1512943

Similar Items

Similar Items