"FAMILIAL DEFECTIVE APOLIPORROTEIN B 100: FREQUENCY OF R3500Q MUTATION OF APOLIPOROTEIN B GENE IN IRANIAN HYPERCHOLESTEROLEMIC PATIENTS"

"FAMILIAL DEFECTIVE APOLIPORROTEIN B 100: FREQUENCY OF R3500Q MUTATION OF APOLIPOROTEIN B GENE IN IRANIAN HYPERCHOLESTEROLEMIC PATIENTS"

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Familial defective apolipoprotein (apo) B 100 (FDB) causes early-onset coronary heart diseases (CHD). It is produced by R3500Q mutation of the apoB gene resulting in decreased binding of LDL to LDL receptor. We screened the apo B gene for R3500Q mutation in 130 hypercholesterolemic patients, among w...

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Bibliographic Details
Main Authors: P. Fard-Esfahani, P. Mohammadi-Torbati, S. Khatami, S. Zeinali, M. Taghikhani M. Allahyari
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2005-06-01
Series:Acta Medica Iranica
Subjects:
Familial defective apolipoprotein
familial hypercholesterolemia
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/2991

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