Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer

The author analyzes an algorithm for identifying and treating w omen with cervical intraepithelial neoplasias (CIN) and microinv asive cancer of the cervix uteri in cases of the hidden area of transformation and in the absence of visible cervical changes. There are excep- tional difficulties of maki...

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Main Author:	L. I. Korolenkova
Format:	Article
Language:	Russian
Published:	ABV-press 2014-08-01
Series:	Opuholi Ženskoj Reproduktivnoj Sistemy
Subjects:	cervical intraepithelial neoplasia microinvasive cancer smear cytological abnormalities screening hybrid capture 2 hypodiagnosis
Online Access:	https://ojrs.abvpress.ru/ojrs/article/view/181

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spelling	doaj-43c1be0a5eb84c018f7d1ca6fa98f7582021-07-29T08:46:48ZrusABV-pressOpuholi Ženskoj Reproduktivnoj Sistemy1994-40981999-86272014-08-0103747810.17650/1994-4098-2011-0-3-74-78197Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancerL. I. Korolenkova0N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowThe author analyzes an algorithm for identifying and treating w omen with cervical intraepithelial neoplasias (CIN) and microinv asive cancer of the cervix uteri in cases of the hidden area of transformation and in the absence of visible cervical changes. There are excep- tional difficulties of making the diagnosis of epithelial damages due to the incomplete reproducibility of cytological abnormal ities and the low informative value of a histological study of scrapes from the cervical canal. To avoid hypodiagnosis, it is justifiable to prefer human papillomavirus testing (Hybrid Capture 2 (HC2)) to repeat smears for the choice of a management tactic. Conization is recommend ed as a diagnostic and/or therapeutic procedure when the viral load is high in over 35-year-old patients with abnormal smears anda hidden transformation area.https://ojrs.abvpress.ru/ojrs/article/view/181cervical intraepithelial neoplasiamicroinvasive cancersmear cytological abnormalitiesscreeninghybrid capture 2hypodiagnosis
collection	DOAJ
language	Russian
format	Article
sources	DOAJ
author	L. I. Korolenkova
spellingShingle	L. I. Korolenkova Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer Opuholi Ženskoj Reproduktivnoj Sistemy cervical intraepithelial neoplasia microinvasive cancer smear cytological abnormalities screening hybrid capture 2 hypodiagnosis
author_facet	L. I. Korolenkova
author_sort	L. I. Korolenkova
title	Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer
title_short	Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer
title_full	Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer
title_fullStr	Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer
title_full_unstemmed	Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer
title_sort	abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer
publisher	ABV-press
series	Opuholi Ženskoj Reproduktivnoj Sistemy
issn	1994-4098 1999-8627
publishDate	2014-08-01
description	The author analyzes an algorithm for identifying and treating w omen with cervical intraepithelial neoplasias (CIN) and microinv asive cancer of the cervix uteri in cases of the hidden area of transformation and in the absence of visible cervical changes. There are excep- tional difficulties of making the diagnosis of epithelial damages due to the incomplete reproducibility of cytological abnormal ities and the low informative value of a histological study of scrapes from the cervical canal. To avoid hypodiagnosis, it is justifiable to prefer human papillomavirus testing (Hybrid Capture 2 (HC2)) to repeat smears for the choice of a management tactic. Conization is recommend ed as a diagnostic and/or therapeutic procedure when the viral load is high in over 35-year-old patients with abnormal smears anda hidden transformation area.
topic	cervical intraepithelial neoplasia microinvasive cancer smear cytological abnormalities screening hybrid capture 2 hypodiagnosis
url	https://ojrs.abvpress.ru/ojrs/article/view/181
work_keys_str_mv	AT likorolenkova abnormalcervicalsmearsintheunchangeduterinecervixdifficultiesinthescreeningdiagnosisandtreatmentofcervicalintraepithelialneoplasiasandmicroinvasivecancer
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Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer

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