DNA Damage Reduces the Quality, but Not the Quantity of Human Papillomavirus 16 E1 and E2 DNA Replication

DNA Damage Reduces the Quality, but Not the Quantity of Human Papillomavirus 16 E1 and E2 DNA Replication

Human papillomaviruses (HPVs) are causative agents in almost all cervical carcinomas. HPVs are also causative agents in head and neck cancer, the cases of which are increasing rapidly. Viral replication activates the DNA damage response (DDR) pathway; associated proteins are recruited to replication...

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Bibliographic Details
Main Authors: Molly L. Bristol, Xu Wang, Nathan W. Smith, Minkyeong P. Son, Michael R. Evans, Iain M. Morgan
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Viruses
Subjects:
papillomaviruses
cancer
replication
etoposide
integration
E1
E2
TopBP1
HPV
Online Access:http://www.mdpi.com/1999-4915/8/6/175

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