Role of Nitric Oxide in the Antipruritic Effect of WIN 55,212-2, a Cannabinoid Agonist

Role of Nitric Oxide in the Antipruritic Effect of WIN 55,212-2, a Cannabinoid Agonist

Introduction: For centuries, cannabinoids are known to be effective in pain relief. Itch is an unpleasant sensation that provokes a desire to scratch. Since itch and pain are two sensations sharing a lot in common, we aimed to investigate whether the cannabinoid agonist WIN 55,212-2 reduces serotoni...

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Bibliographic Details
Main Authors: Oyku Zeynep Gercek, Busra Oflaz, Neslihan Oguz, Koray Demirci, Ozgur Gunduz, Ahmet Ulugol
Format: Article
Language:English
Published: Iran University of Medical Sciences 2020-07-01
Series:Basic and Clinical Neuroscience
Subjects:
cannabinoid system
nitric oxide
pruritus
serotonin
win 55
212-2
Online Access:http://bcn.iums.ac.ir/article-1-1153-en.html

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