Cerebrospinal Fluid <i>α</i>-Synuclein Species in Cognitive and Movements Disorders

Cerebrospinal Fluid <i>α</i>-Synuclein Species in Cognitive and Movements Disorders

Total CSF α-synuclein (t-α-syn), phosphorylated α-syn (pS129-α-syn) and α-syn oligomers (o-α-syn) have been studied as candidate biomarkers for synucleinopathies, with suboptimal specificity and sensitivity in the differentiation from healthy controls. Studies of α-syn species in patients with other...

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Bibliographic Details
Main Authors: Vasilios C. Constantinides, Nour K. Majbour, George P. Paraskevas, Ilham Abdi, Bared Safieh-Garabedian, Leonidas Stefanis, Omar M. El-Agnaf, Elisabeth Kapaki
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Brain Sciences
Subjects:
α-synuclein
cerebrospinal fluid
biomarkers
tau proteins
beta amyloid
parkinsonism
Online Access:https://www.mdpi.com/2076-3425/11/1/119

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