Somatostatin-receptor avidity of pancreatic neuroendocrine tumor thrombus in porto-caval venous systems on 99mTc-Octreotide and posttherapeutic 177Lu-DOTA-TATE scans

• Main Authors: Mahasti Amoui, Reyhane Ahmadi, Mohsen Qutbi, Isa Neshandar Asli
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2021-01-01
• Series: World Journal of Nuclear Medicine
• Subjects: 177lu-dota-tate; 99mtc-octreotide; pancreatic neuroendocrine tumor; somatostatin-receptor; tumor thrombosis
• Online Access: http://www.wjnm.org/article.asp?issn=1450-1147;year=2021;volume=20;issue=3;spage=324;epage=326;aulast=

A 62-year-old woman with a history of abdominal pain presented with multiple hepatic lesions and dilatation of portal, splenic and superior mesenteric veins on the magnetic resonance imaging referred for a 99mTc-octreotide scan. Accordingly, similar octreotide-avid lesions were found as well as an uptake in the epigastric region conforming to the anatomy of the portocaval venous system, compatible with a tumor thrombosis. Then, the patient underwent two cycles of therapy with 177Lu-DOTA-TATE, on that the same appearance was observed. The uptake in the tumor thrombus remained somewhat unchanged, but clinically, a significant improvement of the intractable ascites was achieved.