Partial agonism of taurine at gamma-containing native and recombinant GABAA receptors.
Taurine is a semi-essential sulfonic acid found at high concentrations in plasma and mammalian tissues which regulates osmolarity, ion channel activity and glucose homeostasis. The structural requirements of GABAA-receptors (GABAAR) gated by taurine are not yet known. We determined taurine potency a...
Main Authors: | Olaf Kletke, Guenter Gisselmann, Andrea May, Hanns Hatt, Olga A Sergeeva |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3640040?pdf=render |
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