The role of mesenchymal stem cells in chemotherapy-induced gonadotoxicity

The role of mesenchymal stem cells in chemotherapy-induced gonadotoxicity

Abstract Background The therapeutic potential of bone marrow-derived mesenchymal stem cells (BM-MSCs) against cisplatin-induced nephrotoxicity has been reported, however, its efficacy in gonadotoxicity still has not been addressed. Herein, we investigated the effect of BM-MSCs in cisplatin-induced t...

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Bibliographic Details
Main Authors: Iman O. Sherif, Dina Sabry, Azza Abdel-Aziz, Osama M. Sarhan
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Stem Cell Research & Therapy
Subjects:
Cisplatin
Mesenchymal stem cells
Oxidative stress
Inflammation
Apoptosis
Testicular toxicity
Online Access:http://link.springer.com/article/10.1186/s13287-018-0946-6

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http://link.springer.com/article/10.1186/s13287-018-0946-6

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