Manipulation of TAD reorganization by chemical-dependent genome linking

Manipulation of TAD reorganization by chemical-dependent genome linking

Summary: Reorganization of topologically associated domain (TAD) is considered to be a novel mechanism for cell fate transitions. Here, we present a protocol to manipulate TAD via abscisic acid (ABA)-dependent genome linking. We use this protocol to merge two adjacent TADs and evaluate the influence...

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Bibliographic Details
Main Authors: Jia Wang, Qian Ma, Peihang Fang, Qi Tian, Haopeng Yu, Junyi Sun, Junjun Ding
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:STAR Protocols
Subjects:
Developmental biology
Genomics
MolecularBiology
CRISPR
Stem Cells
Biotechnology and bioengineering
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721005050

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http://www.sciencedirect.com/science/article/pii/S2666166721005050

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