| Summary: | Dengue fever is a common mosquito-borne viral infection endemic in tropical and subtropical
countries. Neurological manifestations in dengue infection are relatively uncommon, and include
encephalitis, encephalopathy, neuromuscular disorders and neuro-ocular disorders. Cranial
mononeuropathy is a rare manifestation of dengue infection. A 40-year-old man was diagnosed with
isolated, unilateral sixth cranial nerve palsy complicating dengue infection. The patient was managed
accordingly, and full ocular recovery was observed. This was the first reported case of isolated sixth
cranial nerve palsy associated with dengue fever in Malaysia. It is important for clinicians to consider
dengue as a differential diagnosis in patients presenting with fever and sixth cranial nerve palsy.
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