Molecular machineries of pH dysregulation in tumor microenvironment: potential targets for cancer therapy

Molecular machineries of pH dysregulation in tumor microenvironment: potential targets for cancer therapy

Introduction: Cancer is an intricate disorder/dysfunction of cells that can be defined as a genetic heterogeneity in human disease. Therefore, it is characterized by several adaptive complex hallmarks. Among them, the pH dysregulation appears as a symbol of aberrant functions within the tumor microe...

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Bibliographic Details
Main Authors: Mohammad Reza Asgharzadeh, Jaleh Barar, Mohammad M. Pourseif, Morteza Eskandani, Mojtaba Jafari Niya, Mohammad Reza Mashayekhi, Yadollah Omidi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2017-06-01
Series:BioImpacts
Subjects:
Cancer
Carbonic anhydrases
Hypoxia
pH dysregulation
Sodium-hydrogen exchanger
Tumor microenvironment
Online Access:http://bi.tbzmed.ac.ir/PDF/bi-7-115.pdf

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