Rapid and High-Throughput Evaluation of Diverse Configurations of Engineered Lysins Using the VersaTile Technique

Rapid and High-Throughput Evaluation of Diverse Configurations of Engineered Lysins Using the VersaTile Technique

Bacteriophage-encoded lysins are an emerging class of antibacterial enzymes based on peptidoglycan degradation. The modular composition of lysins is a hallmark feature enabling optimization of antibacterial and pharmacological properties by engineering of lysin candidates based on lysin and non-lysi...

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Bibliographic Details
Main Authors: Lisa Duyvejonck, Hans Gerstmans, Michiel Stock, Dennis Grimon, Rob Lavigne, Yves Briers
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Antibiotics
Subjects:
lysin
bacteriophage
VersaTile
<i>Klebsiella pneumoniae</i>
protein engineering
Online Access:https://www.mdpi.com/2079-6382/10/3/293

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