Rapid, scalable, and low-cost purification of recombinant adeno-associated virus produced by baculovirus expression vector system
Recombinant adeno-associated viruses (rAAV) are largely used for gene transfer in research, preclinical developments, and clinical trials. Their broad in vivo biodistribution and long-term efficacy in postmitotic tissues make them good candidates for numerous gene transfer applications. Upstream pro...
Main Authors: | Pierre-Olivier Buclez, Gabriella Dias Florencio, Karima Relizani, Cyriaque Beley, Luis Garcia, Rachid Benchaouir |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2016-01-01
|
Series: | Molecular Therapy: Methods & Clinical Development |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2329050116301784 |
Similar Items
-
Simple downstream process based on detergent treatment improves yield and in vivo transduction efficacy of adeno-associated virus vectors
by: Gabriella Dias Florencio, et al.
Published: (2015-01-01) -
A Recombinant Baculovirus Efficiently Generates Recombinant Adeno-Associated Virus Vectors in Cultured Insect Cells and Larvae
by: Yang Wu, et al.
Published: (2018-09-01) -
A simplified purification protocol for recombinant adeno-associated virus vectors
by: Mark Potter, et al.
Published: (2014-01-01) -
Development of new strategies for efficient production and purification of recombinant adeno-associated virus (rAAV) vector /
by: Liu, Xingluo
Published: (1999) -
Purification of baculovirus vectors using heparin affinity chromatography
by: Md Nasimuzzaman, et al.
Published: (2016-01-01)