1, 25-D3 Protects From Cerebral Ischemia by Maintaining BBB Permeability via PPAR-γ Activation

1, 25-D3 Protects From Cerebral Ischemia by Maintaining BBB Permeability via PPAR-γ Activation

The blood-brain barrier (BBB) is a physical and biochemical barrier that maintains cerebral homeostasis. BBB dysfunction in an ischemic stroke, results in brain injury and subsequent neurological impairment. The aim of this study was to determine the possible protective effects of 1, 25-dihydroxyvit...

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Bibliographic Details
Main Authors: Ting Guo, Yanqiang Wang, Yuanfang Guo, Shuguang Wu, Weiwei Chen, Na Liu, Yu Wang, Deqin Geng
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
BBB permeability
1
25-D3
MCAO/R
PPARγ
NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00480/full

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https://www.frontiersin.org/article/10.3389/fncel.2018.00480/full

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