Extreme caution on the use of sirolimus for the congenital hyperinsulinism in infancy patient

Abstract We have recently published on the limited effectiveness of sirolimus as a treatment option for hypoglycaemia as a consequence of hyperinsulinism. Our data oppose the view that mTOR inhibitors provide new opportunities for the treatment of patients with hyperinsulinism. We are not convinced...

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Bibliographic Details
Main Authors: Indraneel Banerjee, Diva De Leon, Mark J. Dunne
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13023-017-0621-5