Mitochondrial permeability transition pore and cancer: molecular mechanisms involved in cell death

Mitochondrial permeability transition pore and cancer: molecular mechanisms involved in cell death

Since its discovery in the 1970s, the mitochondrial permeability transition has been proposed to be a strategic regulator of cell death. Intense research efforts have focused on elucidating the molecular components of the mitochondrial permeability transition because this knowledge may help to bette...

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Bibliographic Details
Main Authors: Paolo ePinton, Massimo eBonora
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Oncology
Subjects:
Apoptosis
Necrosis
Cancer
Pten
Bcl-2
tumors
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00302/full

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