Novel Dual PDK1/AurK-A Inhibitors for Cancer Therapy: Med Chem Evolution and Crystallographic Investigation

Novel Dual PDK1/AurK-A Inhibitors for Cancer Therapy: Med Chem Evolution and Crystallographic Investigation

The struggle to find novel efficacious pharmacological approaches for cancer treatment has led<br />to the identification of several kinases involved in neoplastic genesis and cell development. [...]

Bibliographic Details
Main Authors:	Simona Sestito, Sara Chiarugi, Eleonora Margheritis, Massimiliano Runfola, Simone Bertini, Gianpiero Garau, Simona Rapposelli
Format:	Article
Language:	English
Published:	MDPI AG 2019-08-01
Series:	Proceedings
Subjects:	PDK1/AurK-A inhibitors kinase inhibitors drug discovery medicinal chemistry crystallography cancer therapy
Online Access:	https://www.mdpi.com/2504-3900/22/1/45

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