Novel Dual PDK1/AurK-A Inhibitors for Cancer Therapy: Med Chem Evolution and Crystallographic Investigation

The struggle to find novel efficacious pharmacological approaches for cancer treatment has led<br />to the identification of several kinases involved in neoplastic genesis and cell development. [...]

Bibliographic Details
Main Authors: Simona Sestito, Sara Chiarugi, Eleonora Margheritis, Massimiliano Runfola, Simone Bertini, Gianpiero Garau, Simona Rapposelli
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Proceedings
Subjects:
Online Access:https://www.mdpi.com/2504-3900/22/1/45