SP1 induced long non-coding RNA AGAP2-AS1 promotes cholangiocarcinoma proliferation via silencing of CDKN1A

SP1 induced long non-coding RNA AGAP2-AS1 promotes cholangiocarcinoma proliferation via silencing of CDKN1A

Abstract Background LncRNA can regulate gene at various levels such as apparent genetics, alternative splicing, and regulation of mRNA degradation. However, the molecular mechanism of LncRNA in cholangiocarcinoma is still unclear. This deserves further exploration. Methods We investigated the expres...

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Bibliographic Details
Main Authors: Hao Ji, Juan Wang, Binbin Lu, Juan Li, Jing Zhou, Li Wang, Shufen Xu, Peng Peng, Xuezhen Hu, Keming Wang
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Molecular Medicine
Subjects:
LncRNA
AGAP2-AS1
CCA
EZH2
Biomarker apoptosis
Online Access:https://doi.org/10.1186/s10020-020-00222-x

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