Engineering and application of a biosensor with focused ligand specificity

Engineering and application of a biosensor with focused ligand specificity

Transcriptional biosensors represent powerful tools for the screening of vast strain libraries, but the broad ligand specificity of some transcriptional regulators (TRs) can prohibit such applications. Here authors present the engineering of a LysG-based biosensor with a focused ligand specificity t...

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Bibliographic Details
Main Authors: Dennis Della Corte, Hugo L. van Beek, Falk Syberg, Marcus Schallmey, Felix Tobola, Kai U. Cormann, Christine Schlicker, Philipp T. Baumann, Karin Krumbach, Sascha Sokolowsky, Connor J. Morris, Alexander Grünberger, Eckhard Hofmann, Gunnar F. Schröder, Jan Marienhagen
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18400-0

Internet

https://doi.org/10.1038/s41467-020-18400-0

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